學生研究表現

98年入學

  1. Lin, J. N., Lin, V. C. H., Rau, K. M., Shieh, P. C., Kuo, D. H., Shieh, J. C., . . . Way, T. D. (2010). Resveratrol Modulates Tumor Cell Proliferation and Protein Translation via SIRT1-Dependent AMPK Activation. Journal of Agricultural and Food Chemistry, 58(3), 1584-1592. (IF:2.832)

  2. Lin, J. N., Lin, H. Y., Yang, N. S., Li, Y. H., Lee, M. R., Chuang, C. H., . . . Way, T. D. (2013). Chemical Constituents and Anticancer Activity of Yellow Camellias against MDA-MB-231 Human Breast Cancer Cells. Journal of Agricultural and Food Chemistry, 61(40), 9638-9644. (IF:2.912)

     

  3. Chen, W. C., Lai, Y. A., Lin, Y. C., Ma, J. W., Huang, L. F., Yang, N. S., . . . Way, T. D. (2013). Curcumin Suppresses Doxorubicin-Induced Epithelial-Mesenchymal Transition via the Inhibition of TGF-beta and PI3K/AKT Signaling Pathways in 1.Triple-Negative Breast Cancer Cells. Journal of Agricultural and Food Chemistry, 61(48), 11817-11824. (IF:2.912)

  4. Chen, W. C., Hsu, K. Y., Hung, C. M., Lin, Y. C., Yang, N. S., Ho, C. T., . . . Way, T. D. (2014). The anti-tumor efficiency of pterostilbene is promoted with a combined treatment of Fas signaling or autophagy inhibitors in triple negative breast cancer cells. Food & Function, 5(8), 1856-1865. (IF:2.686)

     

  5. Yu, Y. L., Chou, R. H., Chen, L. T., Shyu, W. C., Hsieh, S. C., Wu, C. S., . . . Hung, M. C. (2011). EZH2 Regulates Neuronal Differentiation of Mesenchymal Stem Cells through PIP5K1C-dependent Calcium Signaling. Journal of Biological Chemistry, 286(11), 9657-9667. (IF:4.651)

  6. Wu, C. S., Yen, C. J., Chou, R. H., Li, S. T., Huang, W. C., Ren, C. T., . . . Yu, Y. L. (2012). Cancer-Associated Carbohydrate Antigens as Potential Biomarkers for Hepatocellular Carcinoma. Plos One, 7(7). (IF:3.73)

  7. Yu, Y. L., Chou, R. H., Shyu, W. C., Hsieh, S. C., Wu, C. S., Chiang, S. Y., . . . Hung, M. C. (2013). Smurf2-mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic stroke. Embo Molecular Medicine, 5(4), 531-547. (IF:8.665)

  8. Wu, C. S., Lee, T. Y., Chou, R. H., Yen, C. J., Huang, W. C., Wu, C. Y., & Yu, Y. L. (2014). Development of a Highly Sensitive Glycan Microarray for Quantifying AFP-L3 for Early Prediction of Hepatitis B Virus-Related Hepatocellular Carcinoma. Plos One, 9(6). doi:ARTN e99959-10.1371/journal.pone.0099959 (IF:3.234)

  9. Wu, C. S., Yen, C. J., Chou, R. H., Chen, J. N., Huang, W. C., Wu, C. Y., & Yu, Y. L. (2014). Downregulation of microRNA-15b by hepatitis B virus X enhances hepatocellular carcinoma proliferation via fucosyltransferase 2-induced Globo H expression. International Journal of Cancer, 134(7), 1638-1647. (IF:5.531)

     

  10. Ma, H. T., Sriyam, S., Sinchaikul, S., Tsai, H. Y., Phutrakul, S., & Chen, S. T. (2013). Proteomics Characterization of Haptoglobin Alpha-2 Subunit in Non-Small Cell Lung Cancer Serum and Various Human Materials. J Proteomics Bioinform, 6, 187-196. doi:10.4172/jpb.1000280 (IF:2.56)

  11. Ma, H. T., Hsieh, J. F., & Chen, S. T. (2015). Anti-diabetic effects of Ganoderma lucidum. Phytochemistry, 114, 109-113. (IF:2.779)

     

  12. Hsieh, C. C., Shyr, Y. M., Liao, W. Y., Chen, T. H., Wang, S. E., Lu, P. C., . . . Shen, C. N. (2017). Elevation of beta-galactoside alpha 2,6-sialyltransferase 1 in a fructose-responsive manner promotes pancreatic cancer metastasis. Oncotarget, 8(5), 7691-7709. (IF:5.168)

     

  13. Chen, S. C., Shih, C. M., Tseng, G. C., Cheng, W. E., Chiou, J., Hsiao, M., . . . Chen, C. Y. (2011). Vascular Endothelial Growth Factor C as a Predictor of Early Recurrence and Poor Prognosis of Resected Stage I Non-small Cell Lung Cancer. Annals Academy of Medicine Singapore, 40(7), 319-324. (IF:1.362)

  14. Hong, C. C., Chen, P. S., Chiou, J., Chiu, C. F., Yang, C. Y., Hsiao, M., . . . Su, J. L. (2014). miR326 Maturation Is Crucial for VEGF-C-Driven Cortactin Expression and Esophageal Cancer Progression. Cancer Research, 74(21), 6280-6290. (IF:8.556)

  15. Yang, Y. F., Jan, Y. H., Liu, Y. P., Yang, C. J., Su, C. Y., Chang, Y. C., Lai, T. C., Chiou, J., . . . Hsiao, M. (2014). Squalene Synthase Induces Tumor Necrosis Factor Receptor 1 Enrichment in Lipid Rafts to Promote Lung Cancer Metastasis. American Journal of Respiratory and Critical Care Medicine, 190(6), 675-687. (IF:13.118)

  16. Su, C. Y., Liu, Y. P., Yang, C. J., Lin, Y. F., Chiou, J., Chi, L. H., . . . Hsiao, M. (2015). Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer. Plos One, 10(7). (IF:3.057)

  17. Chiou, J., Su, C. Y., Jan, Y. H., Yang, C. J., Huang, M. S., Yu, Y. L., & Hsiao, M. (2017). Decrease of FSTL1-BMP4-Smad signaling predicts poor prognosis in lung adenocarcinoma but not in squamous cell carcinoma. Scientific Reports, 7. (IF:4.122)

  18. Kuo, T. C., Tan, C. T., Chang, Y. W., Hong, C. C., Lee, W. J., Chen, M. W., Jeng, Y.M., Choiu, J. . . . Kuo, M. L. (2017). Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility (vol 123, pg 1082, 2013). Journal of Clinical Investigation, 127(1), 402-402. (IF:12.282)

  19. Chiou, J., Chang, Y. C., Jan, Y. H., Tsai, H. F., Yang, C. J., Huang, M. S., . . . Hsiao, M. (2019). Overexpression of BZW1 is an independent poor prognosis marker and its down-regulation suppresses lung adenocarcinoma metastasis. Scientific Reports, 9. (IF:4.011)

     

  20. Liu, C. M., Hsieh, C. L., He, Y. C., Lo, S. J., Liang, J. A., Hsieh, T. F., . . . Sung, S. Y. (2013). In Vivo Targeting of ADAM9 Gene Expression Using Lentivirus-Delivered shRNA Suppresses Prostate Cancer Growth by Regulating REG4 Dependent Cell Cycle Progression. Plos One, 8(1). (IF:3.534)

  21. Liu, C. M., Hsieh, C. L., Shen, C. N., Lin, C. C., Shigemura, K., & Sung, S. Y. (2016). Exosomes from the tumor microenvironment as reciprocal regulators that enhance prostate cancer progression. International Journal of Urology, 23(9), 734-744. (IF:1.941)


99年入學

  1. Tseng, W. C., Wang, L. Y., Wu, T. S., & Wong, F. F. (2011). 'One-flask' synthesis to 3,5-disubstituted 1,2,4-triazoles from aldehydes with hydrazonoyl hydrochlorides via 1,3-dipolar cycloaddition. Tetrahedron, 67(29), 5339-5345. (IF: 3.025)

  2. Wang, L. Y., Tseng, W. C., Wu, T. S., Kaneko, K., Takayama, H., Kimura, M., . . . Wong, F. F. (2011). Synthesis and antiproliferative evaluation of 3,5-disubstituted 1,2,4-triazoles containing flurophenyl and trifluoromethanephenyl moieties. Bioorganic & Medicinal Chemistry Letters, 21(18), 5358-5362 (IF: 2.338).

  3. Wang, L. Y., Uramaru, N., & Wong, F. F. (2014). Synthesis of pyrazolo[3,4-b]pyrrolo[3,4-d]pyridine derivatives via Aza-Diels-Alder reaction: evaluation of torsion effect of pyrazoylimines. Tetrahedron, 70(41), 7439-7444. (IF: 2.641)

  4. Wang, L. Y., Tsai, H. J., Lin, H. Y., Kaneko, K., Cheng, F. Y., Shih, H. S., . . . Huang, J. J. (2014). One-flask synthesis of 1,3,5-trisubstituted 1,2,4-triazoles from nitriles and hydrazonoyl chlorides via 1,3-dipolar cycloaddition. Rsc Advances, 4(27), 14215-14220. (IF: 3.84)

  5. Wang, L. Y., Chang, E. C., Yeh, M. Y., Chung, Y. H., Huang, J. J., & Wong, F. F. (2014). Synthesis of 1,3,4-Oxadiazole-Based Aromatic and Heterocyclic/Phenylpyrazole Derivatives. Heteroatom Chemistry, 25(3), 171-177. (IF: 1.203)

     

  6. Yu, Y. L., Yu, S. L., Su, K. J., Wei, C. W., Jian, M. H., Lin, P. C., . . . Chen, Y. L. S. (2010). Extended O-6-Methylguanine Methyltransferase Promoter Hypermethylation Following n-Butylidenephthalide Combined with 1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU) on Inhibition of Human Hepatocellular Carcinoma Cell Growth. Journal of Agricultural and Food Chemistry, 58(3), 1630-1638. (IF:2.816)

  7. Su, K. J., Chen, C. J., Wei, C. W., Lin, C. J., Yiang, G. T., Lin, S. Z., . . . Yu, Y. L. (2011). Synergistic anti-tumor activity of isochaihulactone and paclitaxel on human lung cancer cells. Febs Journal, 278, 216-216. (IF:2.912)

  8. Yu, Y. L., Su, K. J., Hsieh, Y. H., Lee, H. L., Chen, T. Y., Hsiao, P. C., & Yang, S. F. (2013). Effects of EZH2 Polymorphisms on Susceptibility to and Pathological Development of Hepatocellular Carcinoma. Plos One, 8(9). (IF:3.234) 

  9. Yu, Y. L., Su, K. J., Hsieh, M. J., Wang, S. S., Wang, P. H., Weng, W. C., & Yang, S. F. (2014). Impact of EZH2 Polymorphisms on Urothelial Cell Carcinoma Susceptibility and Clinicopathologic Features. Plos One, 9(4). (IF:3.534)

     

  10. Yeh HC, Lin YT, Ting IW, Huang HC, Chiang HY, Chung CW, Chang SN, Kuo CC. Variability of red blood cell size predicts all-cause mortality, but not progression to dialysis, in patients with chronic kidney disease: A 13-year pre-ESRD registry-based cohort. Clin Chim Acta. 2019 Oct;497:163-171. doi: 10.1016/j.cca.2019.07.035. Epub 2019 Jul 30. (IF:2.615)

  11. Wu CM, Su FH, Wang WC, Lin CP, Kamiza AB, Chang SN, Yeh CC. Association of chronic hepatitis B virus infection with age-related macular degeneration. Acta Ophthalmol. 2019 Aug;97(5):e713-e718. doi: 10.1111/aos.14032. Epub 2019 Jan 28. (IF:3.362)

  12. Tsai CW, Huang HC, Chiang HY, Chung CW, Chang SN, Chu PL, Kuo CC. Longitudinal lipid trends and adverse outcomes in patients with CKD: a 13-year observational cohort study. J Lipid Res. 2019 Mar;60(3):648-660. doi: 10.1194/jlr.P084590. Epub 2019 Jan 14.( IF:4.483)

  13. Tang KT, Chen YM, Chang SN, Lin CH, Chen DY. Psoriatic patients with chronic viral hepatitis do not have an increased risk of liver cirrhosis despite long-term methotrexate use: Real-world data from a nationwide cohort study in Taiwan. J Am Acad Dermatol. 2018 Oct;79(4):652-658. doi: 10.1016/j.jaad.2018.05.004. Epub 2018 May 10.( IF:8.277)

  14. Huang YF, Chiang HY, Chang SN, Chiang FF. Type of adjuvant chemotherapy and treatment frequency in survival outcome of patients with colorectal liver metastases who underwent liver metastasectomy: an 8-year cohort study in Taiwan. Int J Colorectal Dis. 2018 Jul;33(7):985-989. doi: 10.1007/s00384-018-3034-6. Epub 2018 Apr 4. (IF: 2.108)

  15. Cheng YY, Kao CL, Lin SY, Chang ST, Wei TS, Chang SN, Lin CH. Effect of an increased dosage of statins on spinal degenerative joint disease: a retrospective cohort study. BMJ Open. 2018 Feb 8;8(2):e017442. doi: 10.1136/bmjopen-2017-017442. (IF: 2.496)

  16. Yeh CC, Lai CY, Chang SN, Hsieh LL, Tang R, Sung FC, Lin YK. Polymorphisms of MTHFR C677T and A1298C associated with survival in patients with colorectal cancer treated with 5-fluorouracil-based chemotherapy. Int J Clin Oncol. 2017 Jun;22(3):484-493. doi: 10.1007/s10147-016-1080-z. Epub 2017 Jan 2. (IF:2.879)


100年入學

  1. Chen, Y. F., Lin, Y. C., Huang, P. K., Chan, H. C., Kuo, S. C., Lee, K. H., & Huang, L. J. (2013). Design and synthesis of 6,7-methylenedioxy-4-substituted phenylquinolin-2(1H)-one derivatives as novel anticancer agents that induce apoptosis with cell cycle arrest at G2/M phase. Bioorganic & Medicinal Chemistry, 21(17), 5064-5075. (IF:2.793)

  2. Chen, Y. F., Lin, Y. C., Morris-Natschke, S. L., Wei, C. F., Shen, T. C., Lin, H. Y., . . . Huang, L. J. (2015). Synthesis and SAR studies of novel 6,7,8-substituted 4-substituted benzyloxyquinolin-2(1H)-one derivatives for anticancer activity. British Journal of Pharmacology, 172(5), 1195-1221. (5.491)

     

  3. Liao, H. F., Lee, C. C., Hsiao, P. C., Chen, Y. F., Tseng, C. H., Tzeng, C. C., . . . Chang, J. G. (2016). TCH1036, a indeno[1,2-c] quinoline derivative, potentially inhibited the growth of human brain malignant glioma (GBM) 8401 cells via suppression of the expression of Suv39h1 and PARP. Biomedicine & Pharmacotherapy, 82, 649-659. (IF:3.457)

  4. Liao, H. F., Lee, H. H., Chang, Y. S., Lin, C. L., Liu, T. Y., Chen, Y. C., . . . Chang, J. G. (2016). Down-regulated and Commonly mutated ALPK1 in Lung and Colorectal Cancers. Scientific Reports, 6. (IF:4.259)

     

  5. Huang, W. C., Hsu, S. C., Huang, S. J., Chen, Y. J., Hsiao, Y. C., Zhang, W., . . . Hung, M. C. (2013). Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresis. American Journal of Translational Research, 5(4), 441-449. (IF:3.304) 

  6. Hsiao, Y. C., Yeh, M. H., Chen, Y. J., Liu, J. F., Tang, C. H., & Huang, W. C. (2015). Lapatinib increases motility of triple-negative breast cancer cells by decreasing miRNA-7 and inducing Raf-1/MAPK-dependent interleukin-6. Oncotarget, 6(35), 37965-37978. (IF:5.008)

  7. Tu, C. Y., Cheng, F. J., Chen, C. M., Wang, S. L., Hsiao, Y. C., Chen, C. H., . . . Huang, W. C. (2018). Cigarette smoke enhances oncogene addiction to c-MET and desensitizes EGFR-expressing non-small cell lung cancer to EGFR TKIs. Molecular Oncology, 12(5), 705-723. (IF:5.962)


101年入學

  1. Wu, T. K., Wei, C. W., Pan, Y. R., Cherng, S. H., Chang, W. J., Wang, H. F., & Yu, Y. L. (2015). Vitamin C attenuates the toxic effect of aristolochic acid on renal tubular cells via decreasing oxidative stress-mediated cell death pathways. Molecular Medicine Reports, 12(4), 6086-6092. (IF:1.692)

  2. Wu, T. K., Pan, Y. R., Wang, H. F., Wei, C. W., & Yu, Y. L. (2018). Vitamin E (-tocopherol) ameliorates aristolochic acid-induced renal tubular epithelial cell death by attenuating oxidative stress and caspase-3 activation. Molecular Medicine Reports, 17(1), 31-36. (IF:1.851)

  3. Wu, T. K., Liu, H. C., Lin, S. Y., Yu, Y. L., & Wei, C. W. (2018). Extracts from guava fruit protect renal tubular endothelial cells against acetaminophen-induced cytotoxicity. Molecular Medicine Reports, 17(4), 5544-5551. (IF:1.851)

  4. Wu, T. K., Lim, P. S., Jin, J. S., Wu, M. Y., & Chen, C. H. (2018). Impaired Gut Epithelial Tight Junction Expression in Hemodialysis Patients Complicated with Intradialytic Hypotension. Biomed Research International. (IF:2.18)

  5. Wu, T. K., Wei, C. W., Pan, Y. R., Hsu, R. J., Wu, C. Y., & Yu, Y. L. (2019). The uremic toxin p-cresyl sulfate induces proliferation and migration of clear cell renal cell carcinoma via microRNA-21/HIF-1 alpha axis signals. Scientific Reports, 9. (4.011)

     

  6. Fang-Pin Chang, Shyh-Shyun Huang, Tzong-Huei Lee, Chi-I Chang, Tzong-Fu Kuo, Guan-Jhong Huang, and Yueh-Hsiung Kuo. Four New Iridoid Metabolites Have Been Isolated From the Stems of Neonauclea reticulata (Havil.) Merr. With Anti-Inflammatory Activities on LPS-Induced RAW264.7 Cells. Molecules 2019, 24, 4271; doi:10.3390/molecules24234271(IF 3.060)

  7. Fang-Pin Chang, Wei Chao, Sheng-Yang Wang, Hui-Chi Huang, Ping-Jyun Sung, Jih-Jung Chen, Ming-Jen Cheng, Guan-Jhong Huang, and Yueh-Hsiung Kuo. Three New Iridoid Derivatives Have Been Isolated from the Stems of Neonauclea reticulata (Havil.) Merr. with Cytotoxic Activity on Hepatocellular Carcinoma Cells. Molecules 2018, 23, 2297; doi:10.3390/molecules23092297 (IF 3.060)

  8. Fang-Pin Chang, Chien-Chih Chen, Hui-Chi Huang, Sheng-Yang Wang, Jih-Jung Chen, Chang-Syun Yang, Chung-Yi Ou, Jin-Bin Wu, Guan-Jhong Huang, and Yueh-Hsiung Kuo. A New Bithiophene from the Root of Echinops grijsii. Natural Product Communications Vol. 10 (0) 2015. PMID: 26882687 (IF 0.884)


102年入學

  1. Chen, J. Y., Chen, Y. J., Yen, C. J., Chen, W. S., & Huang, W. C. (2016). HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3. Oncotarget, 7(1), 473-489. (IF:5.168)

  2. Chen, Y. C., Lu, M. C., El-Shazly, M., Lai, K. H., Wu, T. Y., Hsu, Y. M., . . . Liu, Y. C. (2018). Breaking down Leukemia Walls: Heteronemin, a Sesterterpene Derivative, Induces Apoptosis in Leukemia Molt4 Cells through Oxidative Stress, Mitochondrial Dysfunction and Induction of Talin Expression. Marine Drugs, 16(6). (IF:3.772)

  3. Chen, Y. C., Liu, Y. C., El-Shazly, M., Wu, T. Y., Chang, J. G., & Wu, Y. C. (2019). Antrodia cinnamomea, a Treasured Medicinal Mushroom, Induces Growth Arrest in Breast Cancer Cells, T47D Cells: New Mechanisms Emerge. International Journal of Molecular Sciences, 20(4). (IF:4.183)

     

  4. Ping-Chen Tu, Yu-Chia Liang, Ming-Ching Kao, Louis Kuoping Chao, Mei-Hwei Tseng, Te-Ling Lu, Ping-Jyun Sung, Yueh-Hsiung Kuo. Phenylpropanoids and lignoids from the whole plant of Vaccinium emarginatum and their cytotoxicity against prostate cancer cells. Nat Prod Res. 2019 Sep 9;1-9. doi: 10.1080/14786419.2019.1655412. PMID: 31496280 DOI: 10.1080/14786419.2019.1655412 (2018IF 1.999)

  5. Ping-Chen Tu, Han-Chun Tseng, Yu-Chia Liang, Guan-Jhong Huang, Te-Ling Lu, Tzong-Fu Kuo, Yueh-Hsiung Kuo. Phytochemical Investigation of Tradescantia Albiflora and Anti-Inflammatory Butenolide Derivatives. Molecules. 2019 Sep 13;24(18):3336. doi: 10.3390/molecules24183336.PMID: 31540241. PMCID: PMC6767271. (2018 IF 3.060)

  6. Ping-Chen Tu, Chih-Ju Chan, Yi-Chen Liu, Yueh-Hsiung Kuo, Ming-Kuem Lin, Meng-Shiou Lee. Bioactivity-Guided Fractionation and NMR-Based Identification of the Immunomodulatory Isoflavone From the Roots of Uraria crinita (L.) Desv. Ex DC. Foods. 2019 Nov 3;8(11):543. doi: 10.3390/foods8110543. PMID: 31684126. PMCID: PMC6915426. (2018 IF 3.011)

  7. Ping-Chen Tu, Yu-Chia Liang, Guan-Jhong Huang, Hui-Chi Huang, Ming-Ching Kao, Te-Ling Lu, Yueh-Hsiung Kuo. New Flavonoids, Emarginin A-C From Vaccinium Emarginatum Hayata. Fitoterapia. 2020 Mar;141:104446. doi: 10.1016/j.fitote.2019.104446. Epub 2019 Nov 29. PMID: 31790770. (2018 IF 2.431)

     

  8. Chen, J. Y., Chen, Y. J., Yen, C. J., Chen, W. S., & Huang, W. C. (2016). HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3. Oncotarget, 7(1), 473-489. (IF:5.168)


103年入學

  1. Tu, Chih-Yen、Cheng, Fang-Ju*、Chuan-Mu Chen*、Shu-Ling Wang*、Yu-Chun Hsiao、Chen, Chia-Hung、Hsia, Te-Chun、He, Yu-Hao、…、Huang, Wei-Chien*. Cigarette smoke enhances oncogene addiction to c-MET and desensitizes EGFR-expressing non-small cell lung cancer to EGFR TKIs. Molecular Oncology. 12(5):705~723. 2018.05 (Impact Factor:6.574)